June 06, 2014

SMBE 2014 Ancient Genomics

Some interesting titles from the upcoming SMBE 2014 conference:

O-11Genotyping of 390,000 SNPs in more than forty 3,000-9,000 year old humans from the ancient Russian steppe
David Reich*1,2, Nadin Rohland1,2, Swapan Mallick1,2, Iosif Lazaridis1, Eadaoin Harney1, Susanne Nordenfelt1, Qiaomei Fu3, Matthias Meyer3, Dorcas Brown4, David Anthony4, Nick Patterson2
1Harvard Medical School, USA, 2Broad Institute of Harvard and MIT, USA, 3Max Planck Institute for Evolutionary Anthropology, Germany, 4Hartwick College, USA
O-12Statistical Inference of Archaic Introgression In Central African Pygmies
PingHsun Hsieh*1, Jeffrey Wall2, Joseph Lachance3, Sarah Tishkoff3, Ryan Gutenkunst1, Michael Hammer1
1University of Arizona, USA, 2University of California, USA, 3University of Pennsylvania, USA
O-13Patterns of ancient selection in modern humans around candidate sites
Fernando Racimo*1,2, Martin Kuhlwilm2, Montgomery Slatkin1
1University of California - Berkeley, USA, 2Max Planck Institute for Evolutionary Anthropology, Germany
O-14Ancient maize from the American Southwest
Rute R da Fonseca*1, Bruce Smith2, Nathan Wales1, Enrico Cappellini1, Matteo Fumagalli3, Pontus Skoglund4, Anders Albrechtsen1, Jeff Ross-Ibarra5, Tom Gilbert1
1Copenhagen University, Denmark, 2Smithsonian Institution, USA, 3UC Berkeley, USA, 4Uppsala University, Sweden,5UC Davis, USA
O-15The complete genome sequence of a 45,000-year-oldmodern human from Eurasia
Qiaomei Fu*1,2, Bence Viola1,3, Heng Li5,6, Priya Moorjani6, Flora Jay4, Aximu Ayinuer-Petri1, Susan Keates8, Yaroslav V. Kuzmin7, Montgomery Slatkin4, David Reich5,6, Janet Kelso1, Svante Pääbo1
1Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Germany, 2Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences, China, 3Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Germany, 4Department of Integrative Biology, University of California, USA, 5Broad Institute of MIT and Harvard, Cambridge, USA, 6Department of Genetics,Harvard Medical School, USA, 7Institute of Geology & Mineralogy, Siberian Branch of the Russian Academy of Sciences, Russia,8University Village, USA




The whole program appears to be online, so feel free to point to any noteworthy abstracts in the comments.

4 comments:

terryt said...

"The complete genome sequence of a 45,000-year-oldmodern human from Eurasia"

I hope that includes the Y-DNA it had (if male, of course). The mt-DNA will be equally interesting I suppose.

Hector said...

The long awaited Ust-Ishim study is here. They do not reveal his Y-haplogroup nor mt haplo. It says "related to Europeans and Asians".

We have sequenced to high coverage the genome of a femur recently discovered near Ust-Ishim in Siberia. The bone was directly carbon-dated to 45,000 years before present. Analyses of the relationship of the Ust-Ishim individual to present-day humans show that he is closely related to the ancestral population shared between present-day Europeans and present-day Asians. The over-all amount of genomic admixture from Neandertals is similar to that in present-day non-Africans and there is no evidence for admixture from Denisovans. However, the size of the genomic segments of Neandertal ancestry in the Ust-Ishim individual is substantially larger than in present-day individuals. From the size distribution of these segments we estimated that this individual lived about 200-400 generations after the admixture with Neandertals occurred. The age of this genome allows us to directly assess the mutation rate in the different compartments of the human genome. These results will be presented and discussed.

Hector said...

First, my apology for pasting the entire abstract for Ust-Ishim in the previous post.

The abstract was difficult to find in my case because I had not known it was accessible directly by clicking from the list.

Another interesting paper is the analysis of 3-9000 years old samples from the Russian step.

It says the group is related to ANE of Malta boy type and mtDNA is all West Eurasian.

pconroy said...

WOW!!!

Genotyping of 390,000 SNPs in more than forty 3,000-9,000 year old humans from the ancient Russian steppe

That paper is going to be huge!