August 06, 2010

Genome-wide study of Indian men

Not a type of study I usually cover, but it has a hidden gem in Figure 2, reproduced on the left, which shows a PCA plot of Indian men color-coded by religion and language.

The existence of two clusters is kind of obvious, while their interpretation is not as dots of the same color appear in both clusters: a placement of these individuals in a global context might have been useful here. Things are clearer at the top cluster which shows a clear gradient anchored by Punjabi Sikh and Hindu Tamils on either end.

Also of interest is the group of isolated Muslim/Christian individuals on the left which deviate strongly from the mainstream; these probably represent exogenous elements that don't resembe the bulk of the Indian population.

PLoS ONE 5(8): e11961. doi:10.1371/journal.pone.0011961

A Genome-Wide Association Study of the Metabolic Syndrome in Indian Asian Men

Delilah Zabaneh, David J. Balding

Link

2 comments:

South Central Haplo said...

No biggie.
Muslims has some Shiite J2X. Most of the Christians are aligned with Tamil Hindus from south where majority of Christians live.

There might be some Anglo Indian samples that are showing too left.

agnes said...

most Christians are in india hindu converts,so they resemble the local hindu population say hindu tamils similar to christian tamils,marathi christians similar to marathi hindus.i think some of the outliers are anglo-indians,they are british descendants their mother tongue is english.other wise there is no chance for english-mother tongue in india.