tag:blogger.com,1999:blog-7785493.post7009252510919661571..comments2024-01-04T04:11:55.717+02:00Comments on Dienekes’ Anthropology Blog: Reconstructing the ancestral allele value in a Y-STR locusDienekeshttp://www.blogger.com/profile/02082684850093948970noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-7785493.post-47021178704885426662008-09-07T22:29:00.000+03:002008-09-07T22:29:00.000+03:00I have always pretty much used the modal value als...I have always pretty much used the modal value also. But, since my research has concentrated on R1b, I have done some additional studies that help me make better estimates of TMRCA. In R1b we have a discontinuity. I believe it was caused by the great flood, but whatever. I can show that 393 =12 is ancestral to 13 for 393. Higher diversity, longer TMRCA. I have worked with several data sets and shownn that the TMRCA of the set of 13's is often significantly shorter than 12's. For s116+, I get about 6K years difference. This was not readily apparent in the data sets. By a whopping amount 13 is modal. What first got me intrigued was the Tarin Iberian and non-iberian datasets. I noticed that the Iberian, which is older, has a higher percent of 12 than the non-iberian, 3% in the non-iberian and 9% in the iberian, this factor got me thinking this way. So if a value of a dys loci is antecedent, it doesn't mutate to the modal. I know there are back mutations but they are a lesser effect than this.<BR/><BR/>One other study I performed was to separate 391 10/11 entries. In my analysis of the Scottish highlands I found that 11,11 appeared to be the Pictish signature and 10,11 the Scotti (Erainn). In this case, both the Iberian and non iberian data sets have about the same amount of each. I separated the 391 10 and 11 sets of data and this time I could see no difference in TMRCA. The mutation from 10 to 11 or 11 to 10 occurred very early and each has maintained a fairly constant population percentage since then.<BR/><BR/>Other than 393, I have not observed any other dys loci of this nature in R1b.McGhttps://www.blogger.com/profile/03459589185170647441noreply@blogger.com