tag:blogger.com,1999:blog-7785493.post832159730532022537..comments2024-01-04T04:11:55.717+02:00Comments on Dienekes’ Anthropology Blog: Runs of homozygosity, short and longDienekeshttp://www.blogger.com/profile/02082684850093948970noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-7785493.post-32371702686657115052012-08-20T04:49:17.997+03:002012-08-20T04:49:17.997+03:00This is the same problem as linkage disequilibrium...This is the same problem as linkage disequilibrium age estimates of populations. The assumption that recombination occurs similarly in all populations is made, but variation in PRDM9 changes recombination patterns and the percentage of recombination that occurs in hotspots.<br /><br />The shorter ROHs could simple be due to changes in recombination hotspots.Aaronhttps://www.blogger.com/profile/01270554253475715322noreply@blogger.comtag:blogger.com,1999:blog-7785493.post-52177577832214351422012-08-19T19:36:17.205+03:002012-08-19T19:36:17.205+03:00It's probably because they are one of the leas...It's probably because they are one of the least genetically diverse people in the world; heterozygosity decreases away from Africa, and is probably at its minimum there, so even if people don't marry close relatives, they end up having two identical segments of DNADienekeshttps://www.blogger.com/profile/02082684850093948970noreply@blogger.comtag:blogger.com,1999:blog-7785493.post-67603863994697609242012-08-19T19:33:55.440+03:002012-08-19T19:33:55.440+03:00I'm not sure of what to make of the large, lon...I'm not sure of what to make of the large, long ROH on the South Americans. What do you think, Dienekes?swarmintelligencehttps://www.blogger.com/profile/11463655571727068941noreply@blogger.com