tag:blogger.com,1999:blog-7785493.post5370070805264247387..comments2024-01-04T04:11:55.717+02:00Comments on Dienekes’ Anthropology Blog: Erratum on my Y-STR variance work (which, surprisingly further supports its central thesis)Dienekeshttp://www.blogger.com/profile/02082684850093948970noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-7785493.post-77069693316731531802008-09-20T17:08:00.000+03:002008-09-20T17:08:00.000+03:00I have been studying the relationship between the ...I have been studying the relationship between the Chambers mutation rates and the ZUL derived rates I use. One observation is that in most R1b data sets I have observed the number of mutations at 426 and 388 are similar and my rates for the two are within about 10%. Chandler has a 3:1 ratio for 388 over 426. The only way I can make sense of that is that, as he says, he used multiple Hg's, including I. As you have admitted 388 varies across haplogroups. My point is , I have never read an in depth analysis of Chambers technique for extracting data. How did he exclude father/son samples and cousins samples which will increase rates??? So my basic question is: how accurate are Chambers germline rates. As you know ZUL's approach has been subjected to much scrutiny.McGhttps://www.blogger.com/profile/03459589185170647441noreply@blogger.comtag:blogger.com,1999:blog-7785493.post-17182059757591778872008-09-18T13:35:00.000+03:002008-09-18T13:35:00.000+03:00Some comments on TMRCA. 1.In doing TMRCA analysis...Some comments on TMRCA. 1.In doing TMRCA analysis, you converge to a haplotype, who had that haplotype is the question. I believe new lineages may occur whenever a mutation occurs (read that tree line), but the common characteristic of every person in the oldest tree is that they all possess that same first mutation. Clan Gregor is a good example; all "genetic" MacGregors have a 10 at 385a, which is the original mutation. Other mutations occur as the number of descendants grow but they all have that same mutation. Surprisingly, based on analysis, the current clan chieftain has the same haplotype the Patriarch had!!! Now another example, the Kerchner family. Charles claims Frederick is the TMRCA for his family. When I do a TMRCA analysis I converge to his father Adam, the math is saying to me that Adam had the mutation, had one son who had the mutation and then Frederick had three sons and the line became a tree. We may be saying the same thing, but I claim that convergence is to a haplotype and the first person who had that mutation??McGhttps://www.blogger.com/profile/03459589185170647441noreply@blogger.com